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For instance, mild hypomethylation of bone-marrow MSCs amplifies their secretome and outperforms nave cells in cisplatin models, while coupling the same cells with neonatal ovarian aggregates yields an artificial ovary capable of folliculogenesis without uncontrolled proliferation

When NF-B has been released from the IB protein, it is activated and translocates to the nucleus, where it binds to specific DNA sequences called response elements (RE) and expresses the production of proteins and enzymes that cause changes in the physiological metabolism of the cell [190], such as in the inflammatory, immune, and survival responses and the cell proliferation response [191]

Current diet intake was assessed prior to week 1, and during weeks 3 and 6 of the exercise intervention